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Double-blind, multicenter research study on CDP-choline in patients with main senile mental deterioration [Studio multicentrico in doppio cieco con Citicolina nel deterioramento mentale senile primitivo] Invecchiamento Cerebrale e Cerebrovasculopatie Croniche 1988; Berggren, D., Gustafson, Y., Eriksson, B., Bucht, G., Hansson, L. I., Reiz, S., and Winblad, B. Postoperative confusion after anesthesia in elderly patients with femoral neck fractures.


Analg. 1987; 66( 6 ):497 -504. View abstract. Bettini, R. and Gorini, M. [Reaction times during citicoline treatment] Clin. Ter. 2002; 153( 4 ):247 -250. View abstract. Bonavita E, Chioma V, Dall'Oca P, and et al. Double-blind research study on CDP-choline activity in primitive moderate cognitive degeneration cases [Studio in doppio cieco sull'azione della citicolina nel cervello senile] Minerva Psichiatrica 1983; 24:53 -62.


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[Neuropsychological study of the senile brain throughout and after single and combined treatment with deanol and citicoline] Clin. Ter. 6-15-1986; 117( 5 ):387 -398. View abstract. Brown, E. S., Gorman, A. R., and Hynan, L. S. A randomized, placebo-controlled trial of citicoline add-on therapy in outpatients with bipolar affective disorder and cocaine dependence. J Clin.


2007; 27( 5 ):498 -502. View abstract. Campos, E. C., Schiavi, C., Benedetti, P., Bolzani, R., and Porciatti, V. Effect of citicoline on visual skill in amblyopia: preliminary outcomes. Graefes. Arch Clin. Exp. Ophthalmol. 1995; 233( 5 ):307 -312. View abstract. Capurso A, Capurso S, Panza F, and et al. Efficacy of cytidine diphosphate choline in patients affected by persistent cerebrovascular disease.


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Centrone, G., Ragno, G., and Calicchio, G. [Use of citicoline in high does in acute cerebrovascular illness] Minerva Med 3-17-1986; 77( 11 ):371 -373. View abstract. Clark, W. M., Warach, S. J., Pettigrew, L. C., Gammans, R. E., and Sabounjian, L. A. A randomized dose-response trial of citicoline in intense ischemic stroke patients. Citicoline Stroke Study Hall.



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1997; 49( 3 ):671 -678. View abstract. Clark, W. M., Wechsler, L. R., Sabounjian, L. A., and Schwiderski, U. E. A phase III randomized effectiveness trial of 2000 mg citicoline in acute ischemic stroke patients. Neurology. 11-13-2001; 57( 9 ):1595 -1602. View abstract. Clark, W. M., Williams, B. J., Selzer, K. A., Zweifler, R. M., Sabounjian, L. A., and Gammans, R.


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A randomized effectiveness trial of citicoline in patients with acute ischemic stroke. Stroke. 1999; 30( 12 ):2592 -2597. View abstract. Cubells, J. M. and Hernando, C. Clinical trial on the use of cytidine diphosphate choline in Parkinson's disease. Clin. Ther 1988; 10( 6 ):664 -671.  Click Here For Additional Info . D'Orlando, K. J. and Sandage, B. W., Jr. Citicoline (CDP-choline): mechanisms of action and effects in ischemic brain injury.